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Abstract #2149

Implications of B0 and B1 inhomogeneity for bSSFP imaging of hyperpolarized media

Neil James Stewart1 and Jim Michael Wild1

1University of Sheffield, Sheffield, United Kingdom

The effect of B0 and B1 transmit inhomogeneity on 3D bSSFP lung imaging with hyperpolarized 129Xe was simulated using flip angle and off-resonance frequency maps in combination with the matrix product operator approach to predict 129Xe magnetization dynamics and associated bSSFP signal distributions. B1-related signal drop-off was predicted in posterior and some anterior regions, whilst central regions were generally robust to flip angle variations. Regions of high off-resonance frequency near the diaphragm resulted in low simulated bSSFP signal, corresponding spatially to banding artifact locations. When combined, the two factors led to mean bSSFP image intensity variations ~15-20%.

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