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Abstract #2172

Using intravoxel incoherent motion method to evaluate the effect of butylphthalide in middle cerebral artery occlusion rat model

Dandan Zheng1, Baohong Wen2, Baoqiong Zhao2, and Jingliang Cheng2

1MR Research China, GE Healthcare, Beijing, People's Republic of China, 2Department of MRI, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China

Stroke is the third leading cause of death in industrialized countries and the most frequent cause of acquired adult. Butylphthalide has been shown to have protective effects against ischemic stroke. This study would like to observe the temporal evolution of parameters calculated by IVIM model in an experimental middle cerebral artery occlusion (MCAO) rat model, and how the butylphthalide effect the physiological changes.

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