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Abstract #2317

Network-dependent changes in functional connectivity at 7 tesla in young adults with Down syndrome

Katherine A Koenig1, Se-Hong Oh1, Melissa R Stasko2, Emma Lissemore2, Elizabeth Roth2, Anne Birnbaum2, Thomas Scheidemantel3, Hudson Taylor2, Nancy Roizen3, Stephen Ruedrich3, Mark Lowe1, and Alberto Costa2

1Imaging Institute, The Cleveland Clinic, Cleveland, OH, United States, 2Case Western Reserve University, Cleveland, OH, United States, 3University Hospitals, Cleveland, OH, United States

This works uses 7 tesla MRI to assess resting state functional connectivity (rs-fMRI) in young adults with Down syndrome (DS). As compared to matched controls, individuals with DS show increased rs-fMRI in the default mode network, but decreased rs-fMRI in a network related to executive function.

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