We aim to investigate the effect of the topology of brain microbleeds (BMBs), lobar (n = 32) versus deep/infratentorial (n = 31), on structural brain network in patients with TIA or first-time stroke. Our results demonstrated that the efficiency of the local and global networks of both BMB cohorts were lower compared to controls (n = 31), and that only the load of the patients with lobar BMBs was strongly associated with decrease in the efficiency of local and global networks independent of vascular risk factors. These findings suggested that lobar and deep BMBs likely have distinct pathophysiological underpinnings.
This abstract and the presentation materials are available to members only; a login is required.