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Abstract #2918

Quantitative Evaluation of Treatment Response to Early Concurrent Chemoradiotherapy with Multi-parametric MRI in Esophageal Cancer

Tieming Xie1, Guoliang Shao1, Lulu Liu2, Jun Yang3, and Peipei Pang4

1Radiology, Zhejiang cancer hospital, hangzhou, People's Republic of China, 2The second clinical medical college, Zhejiang Chinese Medical University, hangzhou, People's Republic of China, 3Life Sciences, GE Healthcare, Shanghai, People's Republic of China, 4Life Sciences, GE Healthcare, hangzhou, People's Republic of China

The best dose of concurrent chemoradiotherapy for esophageal cancer exists individual difference because of tumor heterogeneity. The treatment will be more predictable if we can assess the chemoradiotherapy earlier, which will be helpful in early intervention for optimization of treatment plan, treatment time and improvement of overall survival. Multi-parametric MRI is gradually used for evaluating tumor treatment, and provides earlier and more information than conventional MRI. In this study, we used Ktrans value (derived from DCE-MRI) and ADC value (derived from DWI) to assess treatment response after the fifth concurrent chemoradiotherapy in esophageal cancer.

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