Very long acquisition times is the most important limitation against performing 31P magnetic resonance spectroscopic imaging (MRSI) in clinic environments. To overcome this limitation we show the feasibility of implementing in vivo highly accelerated 31P-MRSI combining flyback echo planar spectroscopic imaging (EPSI) and compressed sensing (CS) achieving a 12x12 matrix over a 24 cm field of view (FOV) in less than 6 minutes. Due to the denoising nature of CS the resultant SNR was also improved using this approach.
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