Abstract #2935

Dynamic 31P spectroscopy during superimposed electrical muscle stimulation and volitional contraction for enhanced metabolic response in the skeletal muscle

Francesco Santini^1,2, Dirk Fischer³, Oliver Bieri^1,2, and Xeni Deligianni^1,2

¹Division of Radiological Physics, University of Basel Hospital, Basel, Switzerland, ²Department of Biomedical Engineering, University of Basel, Basel, Switzerland, ³Pediatric Neurology, UniversitätsKinderspital beider Basel (UKBB), Basel, Switzerland

Dynamic 31P spectroscopy of the skeletal muscle can provide useful insight into its energy metabolism. However, in order to see dynamic changes in metabolites, a minimum threshold of physical exercise is necessary. In this work, we present a system that uses electrical muscle stimulation superimposed to volitional muscle contraction in order to enhance the metabolic response of the muscle in the same workload condition. This method can have potential application to patients that are unable to voluntarily exert sufficient work for a dynamic spectroscopy investigation.

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