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Abstract #2977

Evaluation of the amygdala and the anterior cingulate cortex by single voxel proton MR spectroscopy in patients with post-traumatic stress disorder after earthquake

Xiaorui Su1, Weina Wang1, Qiyong Gong1, and Qiang Yue1

1Huaxi MR Research Center, Department of Radiology, West China Hospital of Sichuan University, chengdu, People's Republic of China

In order to explore the changes of metabolites in the amygdala and the anterior cingulate of PTSD after earthquake, MR spectroscopy was applied. MRS showed higher ml and NAA levels in ACC, higher NAA levels in the right amygdala of PTSD group as compared to healthy controls. Besides, both in PTSD and healthy controls, NAA+NAAG levels were higher in the left amygdala than the right. And our results indicate there are some metabolic changes in amygdala and ACC of PTSD subjects. Whether combining depressive disorders, cause of PTSD and types of traumatic causes may have contributed to the inconsistency.

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