Abstract #2991

Gannet 3.0: Developing post-processing tools for accelerated J-difference editing

Muhammad Gulamabbas Saleh^1,2, Georg Oeltzschner^1,2, Mark Mikkelsen^1,2, Nicolaas A.J. Puts^1,2, and Richard A.E. Edden^1,2

¹Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, United States, ²F. M. Kirby Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States

Initially conceived as a MATLAB-based batch-processing tool for GABA-edited MRS data acquired with MEGA-PRESS, Gannet 3.0 has been extended to provide new functionalities that can reconstruct data acquired using accelerated editing techniques of multiple metabolites and regions, perform frequency-and-phase correction (FPC), and perform fitting for GSH-edited spectra. We have demonstrated optimal FPC for MEGA-PRESS, MEGA-PRIAM and HERMES data, and fitting for GSH-edited spectra, rendering Gannet 3.0 a suitable post-processing tool for both conventional and accelerated editing.

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