Abstract #3090

Assessing Gas Exchange via Co-Administration of Hyperpolarized [1-13C] Pyruvate and 13C-Bicarbonate

Nicholas Drachman¹, Stephen Kadlecek¹, Hooman Hamedani¹, Mehrdad Pourfathi¹, Sarmad Siddiqui¹, Yi Xin¹, Harrilla Profka¹, Ian Duncan¹, and Rahim Rizi¹

¹Radiology, University of Pennsylvania, Philadelphia, PA, United States

We assess gas exchange in healthy and acutely injured rat lungs by measuring the difference between bicarbonate-to-pyruvate signal-ratio in the right vs. left ventricle of the heart following co-administration of hyperpolarized [1-¹³C] pyruvate and ¹³C-bicarbonate.

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