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Abstract #3090

Assessing Gas Exchange via Co-Administration of Hyperpolarized [1-13C] Pyruvate and 13C-Bicarbonate

Nicholas Drachman1, Stephen Kadlecek1, Hooman Hamedani1, Mehrdad Pourfathi1, Sarmad Siddiqui1, Yi Xin1, Harrilla Profka1, Ian Duncan1, and Rahim Rizi1

1Radiology, University of Pennsylvania, Philadelphia, PA, United States

We assess gas exchange in healthy and acutely injured rat lungs by measuring the difference between bicarbonate-to-pyruvate signal-ratio in the right vs. left ventricle of the heart following co-administration of hyperpolarized [1-13C] pyruvate and 13C-bicarbonate.

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