Intravoxel incoherent motion (IVIM) Diffusion weighted imaging (DWI) showed high clinical value in liver disease evaluation. However, it suffers from signal loss and motion artifacts due to cardiac and respiratory movement, especially in the left lobe. To improve robustness and reproducibility of parameter estimation for IVIM DWI, a novel DWI acqusition technique was introduced, which uses ECG trigger with delay time optimized by the periods of cardiac relative stationary phase. The results showed that the proposed acquisition method improves SNR of DWI data, and the repeatability and stability of IVIM-DWI derived parameters.
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