Hepatic warm ischemia-reperfusion injury (WIRI) is clinically relevant in liver operation. We undertook this study to determine the feasibility of using IVIM for the early diagnosing and grading of hepatic WIRI. Fifty different grades of hepatic WIRI models and control rabbits were examined using a 3T clinical MR scanner, which followed by biochemical and histopathological analysis. There were significant differences of IVIM parameters between different groups. IVIM parameters corresponded well with biochemical parameters. ROC analysis showed the AUC of PF was the largest. This indicated that IVIM is a noninvasive and valuable technique for assessing and grading of hepatic WIRI.
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