Abstract #3411

Distortionless diffusion weighted imaging of the prostate using a multi-shot Turbo Split Spin Echo BLADE sequence with bipolar diffusion gradients

Bart WJ Philips¹, Katharina Paul², Thoralf Niendorf², and Tom WJ Scheenen¹

¹Radiology and Nuclear Medicine, Radboud University Medical Centre Nijmegen, Nijmegen, Netherlands, ²Berlin Ultrahigh Field Facility (BUFF), Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany

Diffusion weighted imaging is an important modality in assessing and detecting prostate cancer, but often suffers from distortion artifact introduced by the EPI readout. We propose a TSE-BLADE split-echo sequence that has the potential for obtaining non-distorted diffusion weighted imaging of the prostate, while obtaining accurate ADC estimations. It is shown to be robust to motion and phase induced artifacts that pester multi-shot diffusion weighted imaging, in phantom measurements and initial patient results.

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