Abstract #3413

Evaluation of Different Diffusion Models and Different B-value Ranges in the Detection of Peripheral Zone Prostate Cancer Using B-values up to 4500 s/mm2

Xiangde Min¹, Zhaoyan Feng¹, Liang Wang¹, and Zhongping Zhang²

¹Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People's Republic of China, ²GE Healthcare China, Guangzhou 510080, China

We performed multi-b value diffusion-weighted imaging (DWI) to compare four phenomenological models (mono-exponential, bi-exponential, stretched exponential, and diffusion kurtosis imaging) with in vivo prostate cancer DWI data. A secondary aim is to compare results for different b-value ranges. The result showed that ADC derived from conventional mono-exponential model high b value (about 3200s/mm2) is an optional parameter for peripheral zone prostate cancer detection.

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