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Abstract #3415

Effects of Echo Time on Diffusion Quantification of Prostate

Zhaoyan Feng1, Xu Yan2, Xiangde Min1, and Liang Wang1

1Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China, 2MR Collaboration NE Asia, Siemens Healthcare, Shanghai, People's Republic of China

We performed multi-b value and multi-TE diffusion imaging with two repetition on healthy human prostate to evaluate the influence of TE on reproducibility and quantification of IVIM diffusion model. The result showed that the Dstar and f parameters of IVIM model had high CVs and particularly high variability, while conventional ADC and D showed high reproducibility and a moderate TE-dependency in the peripheral zone and mild TE-dependency in the central zone. This work suggests that using diffusion parameters as quantitative biomarkers should consider the reproducibility and TE-dependency in clinical studies.

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