Meeting Banner
Abstract #3416

Relationship between diffusion kurtosis imaging and RSI: application to prostate cancer

Roshan Karunamuni1, Joshua Kuperman1, Tyler Seibert1, Natalie Schenker1, Rebecca Rakow-Penner1, Jose Teruel Antolin1, Pal Erik Goa2, David Karow1, Anders Dale1, and Nathan White1

1University of California San Diego, San Diego, CA, United States, 2NTNU, Trondheim, Norway

This study explored the relationship between restriction spectrum imaging (RSI) and diffusion kurtosis imaging. Regions of interest for suspicious lesions and background tissue were identified in four patients with PIRADS 5 lesions. Kurtosis was estimated using either the signal fractions obtained from the RSI fit or the cumulant expansion for the NMR diffusion signal. A strong relationship was observed between RSI-derived restricted signal fraction and RSI-derived kurtosis. The performance of these two metrics was comparable in discriminating between suspicious lesions and background prostate tissue, and both outperformed the cumulant expansion approximation to kurtosis.

This abstract and the presentation materials are available to members only; a login is required.

Join Here