Abstract #3452

Accuracy of ADC measurements with an Ultrashort Echo Time Diffusion Weighted stimulated echo 3D Cones sequence (DW-STEAM 3D Cones UTE)

Paul Baron¹, Dirk H.J. Poot^1,2,3, Piotr A. Wielopolski¹, Edwin H.G. Oei¹, and Juan A. Hernandez-Tamames¹

¹Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, Netherlands, ²Medical Informatics and Radiology, Erasmus Medical Center, Rotterdam, Netherlands, ³Imaging Science and Technology, Delft University of Technology, Delft, Netherlands

Diffusion weighted STEAM with UTE readout is a promising acquisition method to measure diffusion in tissues with short T2 and T2*, such as tendons, ligaments and menisci. However, the accuracy of the ADC obtained with this method has not been studied before. Using experiments and Bloch simulations we show that the ADC can be biased, especially when a short TR is used, and that this bias depends on T1 and T2. Randomization of the diffusion gradient direction reduces the bias, providing clear suggestions to improve acquisition and/or post processing that reduces the ADC bias.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.