Meeting Banner
Abstract #3580

β‑alanine Loaded Hollow Mesoporous Silica Nanospheres: A Potential Contrast Agent for Magnetic Resonance Spectroscopy Imaging of Brain Glioma

Jing Wang1, Jianxun Qu2, Tianyong Xu2, and Zhenwei Yao1

1Radiology, Huashan Hospital of Fudan University, Shanghai, People's Republic of China, 2GE Healthcare, Shanghai, People's Republic of China

The β‑alanine loaded hollow mesoporous silica nanospheres (AMSNs) with a characteristic MRS spectrum are successfully synthesized and used for contrast enhanced magnetic resonance spectroscopy (MRS) imaging of brain glioma. Material characterizations, in vitro and in vivo cytotoxicity studies and contrast enhanced MRS imaging of both subcutaneously transplanted glioma and in situ glioma are conducted with the synthesized AMSNs.

This abstract and the presentation materials are available to members only; a login is required.

Join Here