Abstract #3590

A Feedback System for Molecular Imaging of 19F FDG

Mirko Hrovat¹, James Balschi², Mike Dabaghyan¹, Mark Mattingly³, and Neal Kalechofsky²

¹Mirtech, Inc., Boston, MA, United States, ²Millikelvin Technologies, LLC, Braintree, MA, United States, ³Bruker BioSpin Corp., Billerica, MA, United States

A feedback system used in conjunction with a high concentration spin reservoir demonstrates an enhanced MRI signal from a molecular imaging target at low concentration. Enhanced images of a 10mM 19F FDG target obtained by a modified 3D Flash sequence are shown. Detectability curves reveal that for a 100ul voxel size, an imaging time of ~30 min is required to image 1mM 19F FDG with an SNR of 4.

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