Abstract #3639

Investigating the relation between electrical conduction and tissue composition with proton and sodium MRI

Stefano Mandija¹, Paul W de Bruin², Andrew G Webb², Peter R Luijten¹, and Cornelis AT van den Berg¹

¹Center for Image Sciences, Center for Image Sciences, UMC Utrecht, Utrecht, Netherlands, ²Radiology, Gorter Center for High-field MRI, LUMC Leiden, Leiden, Netherlands

The focus of the presented work is to understand the relation between electrical conductivity and tissue composition in terms of ²³Na concentration and water fraction. This would be relevant to evaluate the potential value of electrical conductivity imaging as a new endogenous biomarker and the validity of accessing conductivity from water content. For this purpose, MR-EPT and waterEPT conductivity reconstructions are performed and compared to network analyzer measurements. To evaluate whether conductivity is directly related to the total sodium concentration in free water, ²³Na images are acquired at 7T and conductivity reconstruction are then performed using the Stogryn’s model.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.