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Abstract #3640

CONtrast Conformed Electrical Properties Tomography (CONCEPT) based on Multi-channel Transmission

Yicun Wang1, Pierre-Francois Van de Moortele2, and Bin He1,3

1Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, United States, 2Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 3Institute for Engineering in Medicine, University of Minnesota, Minneapolis, MN, United States

Magnetic Resonance based Electrical Properties Tomography holds promise to provide valuable information on tissue functional changes, such as Tumorigenesis. We propose a novel technique based on multi-channel transmission to reconstruct quantitative electrical properties maps by exploiting the intermediate contrast information with jointly promoted sparsity. The resultant optimization problem was solved by Alternating Direction Method of Multipliers within seconds. Numerical simulations, phantom and human subject experiments were performed at 7T using a multi-channel transceiver coils array, demonstrating improved accuracy and visual outcome. CONCEPT does not rely on anatomical assumptions, and therefore represents a general approach suitable for broader applications.

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