Due to limited transmit coil volume, refocusing pulses spoil magnetization located around the edge of the coil even with adiabatic pulses. This is a major problem for hyperpolarized 13C MRI, as this can destroy precious magnetization. To overcome this drawback, we propose to use a high bandwidth slice-selective adiabatic pulse to replace the original non-selective pulse. We designed and optimized the pulse via simulation. Then the slice-selective double spin echo sequence was tested on both phantom and in vivo studies.
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