Abstract #3757

Correction of fat artifacts for unbiased CEST-MRI of the human breast at 7 T

Ferdinand Zimmermann¹, Steffen Görke¹, Johannes Breitling¹, Kerstin Klopries², Johannes Windschuh¹, Heinz-Peter Schlemmer², Mark Edward Ladd¹, Daniel Paech², and Peter Bachert¹

¹Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany, ²Division of Radiology, German Cancer Research Center, Heidelberg, Germany

Chemical Exchange Saturation Transfer (CEST) MRI in the mammary gland is affected by the high fat content in the human breast. Chemical shift induced artifacts are visible in the Z-Spectrum. We showed a method to test and verify water-fat separation techniques in vitro. Transfer of the gained insights to realize water-only CEST-MRI in the human breast is currently under investigation.

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