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Abstract #4143

The quantitative susceptibility mapping and non-motor symptoms of patients with early Parkinson disease

Chae Won Shin1, Sun-Won Park2,3, Jee-Young Lee1, Jongho Lee4, Seon Lee5, Jae Myung Kim4, and Jung Hyo Lhim2

1Department of Neurology, SNU-SMG Boramae Medical Center, Seoul, Korea, Republic of, 2Department of Radiology, SNU-SMG Boramae Medical Center, Seoul, Korea, Republic of, 3Department of Radiology, College of Medicine, Seoul National University, 4Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of, 5Department of Mechanical and Aerospace Engineering, Seoul National University, Seoul, Korea, Republic of

This study is to evaluate the impact of quantitative susceptibility mapping (QSM) on regional distribution of iron deposition and its correlations with non-motor symptoms in patients with early Parkinson disease (PD). The QSM values of deep nuclei and clinical data using validated scales were obtained from patients. There were no differences in regional QSM values between patients and controls, and the QSM values were not correlated with any of motor or non-motor symptoms in PD patients. This study suggests that the QSM may not be a sensitive tool enough to use in patients with early PD.

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