This study is to evaluate the impact of quantitative susceptibility mapping (QSM) on regional distribution of iron deposition and its correlations with non-motor symptoms in patients with early Parkinson disease (PD). The QSM values of deep nuclei and clinical data using validated scales were obtained from patients. There were no differences in regional QSM values between patients and controls, and the QSM values were not correlated with any of motor or non-motor symptoms in PD patients. This study suggests that the QSM may not be a sensitive tool enough to use in patients with early PD.
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