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Abstract #4545

Advancing Quantitative Brain Injury Lesion Imaging Using Total Field Inversion QSM

Salil Soman1, Zhe Liu2, Ursula Nemec, Samantha Holdsworth, Keith L Main, Jerome Yesavage, David Hacknkey, Ansgar J Furst, Maheen M Adamson, Yi Wang, Pascal Spincemaille, and Michael Moseley

1Radiology, Harvard Medical School / BIDMC, Boston, MA, United States, 2Cornell University

Traumatic brain injury often results in brain lesions which are subtle. Current conventional MRI techniques (GRE and SWI) are field strength and echo time dependent, causing lesions to possible be missed. QSM methods can overcome this, but with many artifacts and missed lesions due to masking artifacts. TFI QSM can overcome this issue, as we demonstrate in this study of TBI patients.

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Keywords

brainsusceptibilitylesionsfieldmagnitudemappingquantitativeinjurysubjectsdashedarrowsbackgroundhemorrhageinversiontissueartifactscerebralvisiblewhitemaskingsubtle