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Abstract #4563

The brain metabolite change of magnetic resonance spectroscopy for evaluating he Rehabilitation therapy effect of intra-cerebral hemorrhage rat animal model

Sang-Hun Jang1 and Seung-Man Yu2

1Gimcheon University, Gimcheon, Korea, Republic of, 2Gimcheon University, Gimcheon, Korea, Korea, Republic of

The objective of this study were to examine the brain metabolite concentration quantification change by in-vivo 1H-MRS analysis in animal hemorrhage model, and we determined the bio-marker that was shown the effect of exercise treatment in hemorrhage disease. No significant difference in the concentration levels of experimental and control group were observed (p=0.839). There was great significance in revealing that (Glu+Gln)/tCr value was increased, and tCho/tCr concentration level was decrease applying exercise treatment methods on hemorrhage animal model. Therefore, the metabolite concentration change of (Glu+Gln)/tCr and tCho/tCr can be used as a powerful bio-marker that represented an exercise treatment in hemorrhage patients.

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