The objective of this study were to examine the brain metabolite concentration quantification change by in-vivo 1H-MRS analysis in animal hemorrhage model, and we determined the bio-marker that was shown the effect of exercise treatment in hemorrhage disease. No significant difference in the concentration levels of experimental and control group were observed (p=0.839). There was great significance in revealing that (Glu+Gln)/tCr value was increased, and tCho/tCr concentration level was decrease applying exercise treatment methods on hemorrhage animal model. Therefore, the metabolite concentration change of (Glu+Gln)/tCr and tCho/tCr can be used as a powerful bio-marker that represented an exercise treatment in hemorrhage patients.
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