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Abstract #4568

Association between Occluded Extra-cranial Carotid Artery Disease and Arterial Wall Edema in Ipsilateral Petrous Internal Carotid Artery: A 3D MR Vessel Wall Imaging Study

Xiaoyi Chen1,2, Huilin Zhao3, Zechen Zhou4, Le He2, Rui Li2, Chun Yuan2,5, and Xihai Zhao2

1Beijing Institute for Brain Disorders, Capital Medical University, Beijing, People's Republic of China, 2Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, People's Republic of China, 3Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China, 4Philips Research China, Philips Healthcare, Beijing, People's Republic of China, 5Department of Radiology, University of Washington, Seattle, United States

Carotid artery severe stenosis or occlusion will lead to decreases in blood flow and ischemia in downstream arterial segments. It has been shown that ischemia within vessel wall may lead to wall edema which will affect the vascular revascularization after interventional treatment for the severe stenotic or occluded diseases. This study investigated the correlation between extra-cranial carotid artery stenotic diseases and arterial wall edema in ipsilateral petrous internal carotid artery (ICA) using 3D MR vessel wall imaging. We found that proximal ICA severe stenosis was independently associated with wall edema in ispilateral petrous ICA (OR=2.45, 95% CI 1.65-3.63, P<0.001).

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