Abstract #4646

Baseline of Chemical Exchange Saturation Transfer Imaging for Brain

Yuki Kanazawa¹, Masafumi Harada¹, Mitsuharu Miyoshi², Yuki Matsumoto³, Hiroaki Hayashi¹, Toshiaki Sasaki⁴, and Natsuki Ikemitsu⁵

¹Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan, ²Global MR Applications and Workflow, GE Healthcare, ³Graduate school of Health Science, Tokushima University, ⁴School of Health Sciences, Tokushiama University, ⁵School of Health Sciences, Tokushima University

The purpose of this study is to assess the CEST effect and contrast of various brain regions in normal for phase cycle-CEST MR imaging. Subjects were five healthy volunteers. All slice positions were set on the nucleus basalis level. ROIs were set as thalamus, frontal, occipital, putamen, and gray matter on right and left brain hemispheres of each subject There was no significant difference in mean MTR_asym values among each brain region (P > 0.01 for all). CEST effects for normal brain tissue had no dependency on region and/or left-right hemispheres.

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