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Abstract #4646

Baseline of Chemical Exchange Saturation Transfer Imaging for Brain

Yuki Kanazawa1, Masafumi Harada1, Mitsuharu Miyoshi2, Yuki Matsumoto3, Hiroaki Hayashi1, Toshiaki Sasaki4, and Natsuki Ikemitsu5

1Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan, 2Global MR Applications and Workflow, GE Healthcare, 3Graduate school of Health Science, Tokushima University, 4School of Health Sciences, Tokushiama University, 5School of Health Sciences, Tokushima University

The purpose of this study is to assess the CEST effect and contrast of various brain regions in normal for phase cycle-CEST MR imaging. Subjects were five healthy volunteers. All slice positions were set on the nucleus basalis level. ROIs were set as thalamus, frontal, occipital, putamen, and gray matter on right and left brain hemispheres of each subject There was no significant difference in mean MTRasym values among each brain region (P > 0.01 for all). CEST effects for normal brain tissue had no dependency on region and/or left-right hemispheres.

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