Abstract #4647

31P MR Spectroscopic Imaging of the Human Brain at 7T

Jimin Ren¹, Ty Shang², A. Dean Sherry^1,3, and Craig R. Malloy^1,4

¹Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States, ²Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, United States, ³Department of Chemistry, Unversity of Texas at Dallas, Richardson, TX, ⁴VA North Texas Health Care System, Dallas, TX, United States

³¹P MRS is capable of probing cerebral metabolism in vivo, but clinical applications are limited by poor spatial resolution. This study demonstrates that ³¹P MRS imaging (MRSI) at 7T can offer high quality spectral data that enables cross-sectional mapping of various phosphorus-bearing metabolites in normal human brain. In a patient with prior ischemic stroke, high-energy phosphates were depleted and extracellular inorganic phosphate was increased in the stroke lesion.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.