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Abstract #4729

Cardiac-induced pulsatility of blood flow resolved in sub-millimeter cerebral veins using phase contrast MRI at 7 Tesla

Ian D Driver1, Fabrizio Fasano2, and Richard G Wise1

1CUBRIC, School of Psychology, Cardiff University, Cardiff, United Kingdom, 2Siemens Healthcare Ltd, Frimley, Caberley, United Kingdom

We report the first measurement of venous flow pulsatility in cerebral veins with sub-millimeter diameters using phase contrast MRI. This work exploits the increased signal and finer spatial resolution available at 7 Tesla, over lower field strengths. We suggest that the observed venous pulsatility is a passive response to intracranial pressure changes caused by arterial pulsatility. These measurements may be applied to pathology in which there is compromised venous flow, extending such investigations to the smaller cerebral veins and offering a better understanding of the temporal dynamics of cerebral venous flow.

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