The aim of this study was to provide a human-like diabetic monkey model for cardiovascular research. Myocardial function and tissue characterizations were measured by CMR in 14 diabetic and 5 control monkeys. In addition to diastolic dysfunction, minor and moderate diffuse fibrosis was shown in cardiac T1, T1r, ECV, and non-contrast fibrosis index images in all the hearts of all diabetic monkeys, confirmed by histopathology finding in one diabetic monkey.
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