Abstract #4895

Comparison of the Capability for Quantitative Distinguishing Malignant from Benign Pulmonary Nodules among Dynamic First-Pass CE-Perfusion ADCT and MRI and FDG-PET/CT

Yoshiharu Ohno^1,2, Yuji Kishida³, Sinichiro Seki^1,2, Shigeharu Ohyu⁴, Masao Yui⁴, Wakiko Tani⁵, Noriyuki Negi⁵, Katsusuke Kyotani⁵, and Takeshi Yoshikawa^1,2

¹Division of Functional and Diagnostic Imaging Research, Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan, ²Advanced Biomedical Imaging Research Center, Kobe University Graduate School of Medicine, Kobe, Japan, ³Division of Radiology, Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan, ⁴Center for Medical Research and Development, Toshiba Medical Systems Corporation, Otawara, Japan, ⁵Center for Radiology and Radiation Oncology, Kobe University Hospital, Kobe, Japan

Quantification of perfusion parameter from dynamic CE-perfusion MRI at 3T system may be more difficult than that at 1.5T system, and contrast media concentration may have larger influence to measurement error of perfusion parameter on a 3T system. We hypothesized that a bolus injection protocol with appropriately small contrast media volume can provide accurate pulmonary perfusion parameter on dynamic CE-perfusion MRI at a 3T system. The purpose of this study was to determine the appropriate contrast media volume for quantitative assessment of dynamic CE-pulmonary MRI, when compared with dynamic CE-area-detector CT (ADCT) for quantitative evaluation of perfusion within whole lung.

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