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Abstract #4918

Correlation of dedicated breast PET and dynamic contrast MRI: Appearance of breast background parenchyma and breast cancers

Kanae K. Miyake1,2,3, Debra M. Ikeda2, Andrei H. Iagaru2, Andrew Quon2, Bruce L. Daniel2, Jafi A. Lipson2, Sunita Pal2, Erik Mittra2, Haiwei Henry Guo2, Yuji Nakamoto3, Shotaro Kanao3, Masako Kataoka3, and Kaori Togashi3

1Radiology, Rakuwakai Otowa Hospital, Kyoto, Japan, 2Radiology, Stanford University School of Medicine, Stanford, CA, United States, 3Diagnostic Imaging and Nuclear Medicine, Kyoto University Hospital, Kyoto, Japan

A recently developed ring-shaped PET scanner dedicated for breast (dbPET) provides high-resolution 3D images of a breast. We investigated the correlation between dbPET with 18F-fluorodeoxyglucose and dynamic contrast MRI (DCE-MRI) findings in respect to breast background parenchyma and mass-forming breast cancers. Background parenchymal uptake on dbPET was not associated with background parenchymal enhancement on DCE-MRI. Tumor appearance on dbPET was similar to that on DCE-MRI in majority of cases, suggesting improved spatial resolution of dbPET as well as its feasibility for the use of the combined image analysis with DCE-MRI aiming at functional and structural assessment of primary breast tumors.

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