Abstract #5090

GRAPPATINI put to use: How MSK applications benefit from highly undersampled T2 mapping and synthetic contrasts

Marcus Raudner¹, Tom Hilbert^2,3,4, Tobias Kober^2,3,4, Vladimir Juras¹, Ewald Moser⁵, Claudia Kronnerwetter¹, David Stelzeneder⁶, and Siegfried Trattnig¹

¹High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ²Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, ³Department of Radiology, University Hospital (CHUV), Lausanne, Switzerland, ⁴LTS5, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, ⁵Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria, ⁶Department of Orthopaedics, Medical University of Vienna, Vienna, Austria

The quantitative measurement of the T2 relaxation time has been shown to be a useful tool for radiological diagnosis. However, the use of quantitative MRI (qMRI) in clinical routine is often hindered due to long acquisition times. Here, we assess T2 parameters in the lumbar and cervical spine as well as the knee using GRAPPATINI, a model-based accelerated T2 mapping sequence. Additionally, synthetic T2-weighted (T2w) images are derived from the quantitative maps. The T2 maps and synthetic T2w images are compared to conventional T2w and T2 mapping sequences, yielding an overall 5.8-fold time-saving.

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