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Abstract #5090

GRAPPATINI put to use: How MSK applications benefit from highly undersampled T2 mapping and synthetic contrasts

Marcus Raudner1, Tom Hilbert2,3,4, Tobias Kober2,3,4, Vladimir Juras1, Ewald Moser5, Claudia Kronnerwetter1, David Stelzeneder6, and Siegfried Trattnig1

1High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 2Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, 3Department of Radiology, University Hospital (CHUV), Lausanne, Switzerland, 4LTS5, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 5Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria, 6Department of Orthopaedics, Medical University of Vienna, Vienna, Austria

The quantitative measurement of the T2 relaxation time has been shown to be a useful tool for radiological diagnosis. However, the use of quantitative MRI (qMRI) in clinical routine is often hindered due to long acquisition times. Here, we assess T2 parameters in the lumbar and cervical spine as well as the knee using GRAPPATINI, a model-based accelerated T2 mapping sequence. Additionally, synthetic T2-weighted (T2w) images are derived from the quantitative maps. The T2 maps and synthetic T2w images are compared to conventional T2w and T2 mapping sequences, yielding an overall 5.8-fold time-saving.

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