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Abstract #5470

Quantitative MRI of In Vivo Water and Lipid Concentrations with the ERETIC Method

Eric Baetscher1, Thomas M Barbara1, Manoj Sammi1, Krista Vandenborne2, Glenn Walter2, and William D Rooney1

1Advanced Imaging Research Center, Oregon Health & Science University, Portland, OR, United States, 2Department of Physical Therapy, University of Florida, Gainesville, FL, United States

A synthetic radio-frequency (RF) signal, which is received along with the 1H magnetic resonance (MR) signal in magnetic resonance imaging (MRI), is used to determine absolute tissue water and lipid quantities. We show application of this ERETIC method (electronic reference to access in vivo concentration) to musculoskeletal imaging, with the potential to better track disease progression in Duchenne Muscular Dystrophy (DMD), and other muscle pathologies.

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