Abstract #5481

Factors influencing Data Quality in a Multi-Center Breast MR Spectroscopy Trial (ACRIN 6657 Extension)

Patrick J Bolan¹, Benjamin A Herman², Gregory J Metzger¹, Eunhee Kim³, David C Newitt⁴, Savannah Partridge⁵, Michael Garwood¹, Mark A Rosen⁶, and Nola M Hylton⁴

¹Radiology, University of Minnesota, Minneapolis, MN, United States, ²Center for Statistical Sciences, Brown University, Providence, RI, United States, ³National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, United States, ⁴Radiology, University of California, San Francisco, CA, United States, ⁵Radiology, University of Washington, Seattle, WA, United States, ⁶Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, United States

The ACRIN 6657-extension trial, the first multi-center trial using magnetic resonance spectroscopy (MRS) in breast cancer, has completed and its initial results have been recently published. This study reports on the quality of the MRS data and identifies technical and logistic factors that contributed to a lower-than-anticipated data yield.

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