Chloride (Cl-) is next to the cations Na+ and K+ the most abundant non-organic anion in the mammals. Assessment of chlorine’s (35Cl) concentration in tissue could provide further insights into tissue viability in addition to tissue sodium concentration. Yet, low Signal-to-Noise ratio (SNR) is challenging for the RF hardware components. To overcome these challenges, a Transmit-only-Receive-only (ToRo) system for 35Cl MRI/MRS at 9.4T was developed comprised of an actively-decoupled linearly-driven 16 leg low-pass Birdcage transmitter coil combined with two different receiver coils. Substantial SNR gain was reached using receive-only elements compared to the Birdcage coil in TxRx mode.
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