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Abstract #0065

Clinical Imaging Potential of FRONSAC

Nadine Luedicke Dispenza1, Sebastian Littin2, Maxim Zaitsev2, R. Todd Constable3,4, and Gigi Galiana3

1Department of Biomedical Engineering, Yale University, New Haven, CT, United States, 2Department of Diagnostic Radiology, Medical Physics, University Medical Center Freiburg, Freiburg, Germany, 3Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States, 4Department of Neurosurgery, Yale University, New Haven, CT, United States

Despite potential for more flexible and efficient encoding that better complements receiver geometry, the past decade of work with nonlinear gradients (NLGs) has shown relatively modest improvements on accelerated image quality. In this work we present the first experimental evidence that the previously introduced ROtary Nonlinear Spatial ACquisition (FRONSAC) can notably improve accelerated image quality, both in vitro and in humans. Furthermore, this work introduces and demonstrates a number of robust and flexible attributes of this method, which are crucial to reducing scan times in a clinical setting.

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