Abstract #0125

Late gadolinium enhancement of colorectal liver metastases post-chemotherapy is associated with tumour fibrosis and overall survival post-hepatectomy

Helen Cheung¹, Paul J Karanicolas², Eugene Hsieh³, Natalie Coburn², Tishan Maraj¹, Jin J Kim¹, Howaida Elhakim³, Masoom A Haider¹, Calvin Law², and Laurent Milot¹

¹Department of Medical Imaging, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada, ²Department of Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada, ³Department of Pathology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada

Preoperative MRI is routinely used for diagnosis, staging, and operative planning of colorectal liver metastases (CRCLM), but still relatively unexplored for preoperative prognosis. Tumour fibrosis in post-hepatectomy CRCLM specimens is associated with long-term survival and late gadolinium enhancement is associated with tumour fibrosis in other disease processes (eg. cholangiocarcinoma). We performed a retrospective cohort study (n=121) in patients who received a clinical gadolinium-enhanced MRI prior to hepatectomy for CRCLM. We determined that strong enhancement on delayed phase MRI was associated with tumour fibrosis post-hepatectomy and overall survival.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.