Abstract #0126

Human Hyperpolarized 13C MR of Liver and Bone Metastases using both EPSI and EPI Acquisitions

Zihan Zhu^1,2, Jeremy W Gordon¹, Hsin-Yu Chen¹, Eugene Milshteyn^1,2, Daniele Mammoli¹, Lucas Carvajal¹, Peter J Shin¹, Rahul Aggarwal³, Robert Bok¹, John Kurhanewicz¹, Pamela Munster³, and Daniel B Vigneron¹

¹Department of Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States, ²UC Berkeley - UCSF Graduate Program in Bioengineering, UCSF, San Francisco, CA, United States, ³Department of Medicine, UCSF, San Francisco, CA, United States

Hyperpolarized ¹³C metabolic imaging is a powerful technique with proven safety and efficacy for human studies. The goal of this project was to investigate pyruvate metabolism in patients with prostate and breast cancer metastases with both echo-planar spectroscopic imaging (EPSI) and the echo-planar imaging (EPI) acquisitions in the same exam. The results revealed similarly valuable information of up-regulated LDH-catalyzed conversion of pyruvate to lactate with some advantages and differences between the two acquisition methods.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.