Meeting Banner
Abstract #0275

Overestimation of cardiac lactate production due to liver metabolism of hyperpolarized [1-13C] pyruvate

Patrick Wespi1, Jonas Steinhauser1, Grzegorz Kwiatkowski 1, and Sebastian Kozerke1

1Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland

Spectroscopy is widely used in hyperpolarized metabolic experiments due to its simplicity and robustness. In this work, it is shown that with spectroscopic acquisition in rat hearts, the cardiac lactate production is overestimated due to liver metabolism of [1-13] pyruvate. It is demonstrated that this overestimation can be addressed using spatially resolved data.

This abstract and the presentation materials are available to members only; a login is required.

Join Here