Abstract #0558

Novel contrasts at +2.7 ppm, +1.2 ppm, and -1.7 ppm investigated in vivo with high spectral resolution CEST MRI in the human brain at 9.4T

Mark Schuppert¹, Kai Herz¹, Anagha Deshmane¹, and Moritz Zaiss¹

¹High-field Magnetic Resonance Center, Max Planck Institute for Biological Cybernetics, Tuebingen, Germany

Using volumetric snapshot-GRE CEST MRI at 9.4T with high frequency sampling, we were able to separate novel CEST peaks at +2.7 ppm, +1.2 ppm and -1.7 ppm reliably in the CEST-spectrum and showed creation of maps of these CEST MRI contrasts in the healthy human brain to be feasible in vivo.

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