Abstract #0596

Real-Time Resting-state fMRI for Presurgical Mapping in Patients with Brain Tumors

Kishore Vakamudi¹, Mohammad Omar Chohan², Howard Yonas², Mona D Chaney³, and Stefan Posse¹

¹Neurology, Physics and Astronomy, University of New Mexico, Albuquerque, NM, United States, ²Neurosurgery, University of New Mexico, Albuquerque, NM, United States, ³Neurology, University of New Mexico, Albuquerque, NM, United States

We investigated the feasibility of presurgical mapping in patients with brain tumors using real-time rsfMRI analysis methodology in combination with high-speed multi-band EPI. The objective was to map sensorimotor and language resting state networks in the vicinity of brain tumors and to monitor data quality online. We validated this approach in comparison with tfMRI and intra-operative electrocorticography (ECog). The data in patients show a high degree of consistency between resting state connectivity, task-based activation and ECS localization of motor cortex and Broca’s area. Localization of Wernicke’s area was more variable, both in rsfMRI and tfMRI.

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