Abstract #0758

Double DANTE: an improved method for high-resolution intracranial vessel wall imaging

Bram F Coolen¹, Jasper Schoormans¹, Ernst S Kooreman^1,2, Qinwei Zhang³, Olivia Viessmann⁴, Gustav J Strijkers¹, Aart J Nederveen³, Guillaume Gilbert⁵, and Jeroen CW Siero^6,7

¹Department of Biomedical Engineering & Physics, Academic Medical Center, Amsterdam, Netherlands, ²Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, Netherlands, ³Department of Radiology, Academic Medical Center, Amsterdam, Netherlands, ⁴A.A. Martinos Center for Biomedical Imaging, MGH, Harvard Medical School, Boston, MA, United States, ⁵MR Clinical Science, Philips Healthcare, Markham, ON, Canada, ⁶Department of Radiology, Utrecht Medical Center, Utrecht, Netherlands, ⁷Spinoza Centre for Neuroimaging, Amsterdam, Netherlands

We present the use of Double DANTE as an improved method for DANTE prepared 3D TSE imaging of intracranial arteries. DANTE preparation inherently leads to banding artifacts, which become increasingly visible at high-resolution imaging. We show that Double DANTE strongly reduces banding separation without changes in the DANTE pulse train duration, and more importantly, without compromising flow suppression of blood or CSF. Double DANTE therefore enables high-quality intracranial vessel wall MRI at 0.6mm isotropic resolution.

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