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Abstract #0759

Clinical value of dark-blood late gadolinium enhancement without additional magnetization preparation

Robert J. Holtackers1,2, Caroline M. van de Heyning2,3,4, Muhummad S. Nazir2,3, Imran Rashid2,3, Ioannis Ntalas2,3, Haseeb Rahman3,5, René M. Botnar2,6, and Amedeo Chiribiri2

1Department of Radiology, Maastricht University Medical Centre, Maastricht, Netherlands, 2School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 3Department of Cardiology, St Thomas' Hospital, London, United Kingdom, 4Department of Cardiology, Antwerp University Hospital, Antwerp, Belgium, 5British Heart Foundation Centre of Excellence, King's College London, London, United Kingdom, 6Pontificia Universidad Católica de Chile, Escuela de Ingeniería, Santiago, Chile

Late gadolinium enhancement (LGE) MRI often suffers from poor scar-to-blood contrast when used for detection of (sub)endocardial scar due to the bright signal of adjacent blood. We sought to validate a novel dark-blood LGE technique in a large cohort of 250 patients at both 1.5T and 3T. Combining left ventricular blood nulling with phase-sensitive inversion-recovery significantly improved both image quality and diagnostic confidence compared to conventional bright-blood LGE. As no additional magnetization preparation is used, clinical application on current MRI systems is readily available without the need for extensive simulations, software modifications and/or additional training.

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