Meeting Banner
Abstract #0787

Towards short dipolar relaxation time, T1D, MRI

Gopal Varma1, Patricia Coutinho de Souza1, Valentin H Prevost2, Olivier M Girard2, Victor Carvalho2, Samira Mchinda2, Leo Tsai1, Guillaume Duhamel2, Aaron K Grant1, and David C Alsop1

1Division of MR Research, Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States, 2CNRS, CRMBM, UMR 7339, Aix Marseille Universite, Marseille, France

The inhomogeneous magnetization transfer (ihMT) technique has shown myelin sensitivity, and is understood to be dependent on power and the dipolar relaxation time parameter, T1D, which is longer in myelinated tissues. Implementation of ihMT can be adapted to provide a smaller, but non-negligible signal from other, relatively short T1D tissues. Simulations showed a measurable ihMT signal, achieved from fixed low duty cycle MT preparations with high B1 pulses, decayed with pulse width at a rate dependent on T1D. Thus short, high B1 pulses were implemented to acquire ihMT data from ex-vivo samples of rat heart, kidney, and tail tendon, demonstrating the feasibility of short T1D imaging.

This abstract and the presentation materials are available to members only; a login is required.

Join Here