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Abstract #0789

Elliptical Magnetization Transfer: Calculating MT Parameters from the bSSFP Signal Ellipse

Tobias C Wood1, Anna Combes1, and Shaihan Malik2

1Neuroimaging, King's College London, London, United Kingdom, 2Biomedical Engineering, King's College London, London, United Kingdom

Balanced Steady-State Free-Precession images are sensitive to T1, T2, off-resonance and Magnetization Transfer effects. Previously, Gloor et al extracted MT parameters from SSFP data, but required external T1 & B1 maps and did not account for off-resonance effects. Here we show that by incorporating the elliptical method of Shcherbakova et al, B0 can be measured and the need for an external T1 map removed. We present results covering the whole brain at 1.5mm isotropic voxel size acquired in 20 minutes. We also discuss an interesting asymmetry seen in the SSFP ellipse at low flip-angles.

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