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Abstract #0951

High-performance portable spin-exchange optical pumping polarizer for hyperpolarized 129Xe MRI

Graham Norquay1, Guilhem J Collier1, Oliver I Rodgers1, and Jim M Wild1

1University of Sheffield, Sheffield, United Kingdom

There is increasing interest in hyperpolarized (HP) 129Xe MRI for research and clinical imaging questions in the lungs and other organs where dissolved xenon can be used to assess tissue perfusion. With the motivation of increasing the availability of HP 129Xe technology we undertook to design and build a portable 129Xe polarizer. We demonstrate here a compact portable 129Xe polarizer capable of generating 129Xe polarized to ~35% at a production rate of 1.8 L/h. The polarizer is entirely self-contained, requiring only mains electricity at the site of interest.

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