Treatment for women with locally advanced breast cancer (LABC) is determined with inadequate knowledge of the long-term outcome. We evaluated the prognostic value of textural features derived from pre-treatment CE-MRI in 55 LABC patients scheduled for neoadjuvant chemotherapy. Using overall survival at 7-years follow-up as endpoint, textural features derived from post-contrast pre-treatment images were significantly different. Using all textural features as input for multivariate analysis, we achieved a classification accuracy of 72% (p<0.001), which increased to 78% when including traditional prognostic factors (p<0.001). Textural features provide prognostic information, which can complement the stratification of patients to treatment.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords