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Abstract #1190

Focus Correction in MR Thermometry for Precise Targeting in Focused Ultrasound Thalamotomy for Essential Tremor: Statistical Study from 121 Sonications in 7 Patients

Chang-Sheng Mei1, Shenyan Zong2, Bruno Madore3, and Nathan McDannold3

1Physics, Soochow University, Taipei, Taiwan, 2Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, 3Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States

Focused ultrasound thalamotomy was approved by FDA for the treatment of essential tremor under MRI guidance. However, spatial errors in the location of focal spots are often observed and could jeopardize the patient safety if not taken into account. We previously explained the causes of this error and proposed a correction method. Using the method, data associated with 121 sonications from 7 patients were statistically analyzed in the present study. Results show the focus was shifted by 0.05 mm/°C. The size of shift for treating sonication agrees with the value reported in literature.

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